New research reveals this common painkiller doubles heart risk with minimal relief

If you’ve ever been prescribed tramadol for chronic pain, new research may have you rethinking its benefits. A sweeping scientific review has revealed that this commonly used opioid provides only minimal relief for chronic pain, while simultaneously doubling the risk of serious side effects—particularly those affecting your heart.

Key Takeaways

  • Tramadol only slightly reduces chronic pain—below levels deemed clinically important.
  • The risk of serious side effects, especially heart issues, is significantly higher with tramadol.
  • Researchers suggest minimizing use of tramadol and other opioids where possible.

Why Is Tramadol So Popular?

Tramadol is often trusted by doctors for treating moderate to severe pain, thanks to its dual-action as an opioid and because it’s considered “safer” and less addictive than other options. As a result, tramadol prescriptions have surged in recent years, especially in the United States. But this reputation for safety might be misleading.

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What Did the Studies Actually Find?

To get a clear picture of tramadol’s real-world effects, scientists analyzed 19 clinical trials involving over 6,500 people experiencing various forms of chronic pain—including neuropathic pain, osteoarthritis, fibromyalgia, and chronic low back pain. Most participants took tramadol in tablet form, with treatment periods ranging from 2 to 16 weeks.

Minimal Pain Relief Doesn’t Add Up

 

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