Signs You Should Know If You Have This Thing Called Da…
Yellow discoloration of the skin and eyes is often related to liver problems, such as hepatitis or cirrhosis. It is due to an excess of bilirubin in the blood, which the liver cannot process properly.
Possible Causes
Chronic liver disease
Biliary obstruction
Adverse reactions to medications
The presence of thickened, brownish areas in skin folds may indicate insulin resistance, a common precursor to type 2 diabetes.
This condition is known as acanthosis nigricans.

Chronic facial redness, with visible vessels or inflammatory flare-ups, may be a sign of rosacea. If lesions appear on other parts of the body, they may be associated with allergic reactions, infections, lupus, or even autoimmune diseases.
Although not skin itself, nails are part of the integumentary system. Brittle nails, with dark lines or changes in shape, may indicate nutritional deficiencies, heart disease, or thyroid problems.
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