This ends insulin resistance (in days, not years)
The risks are serious. While we’re often conditioned to fear LDL cholesterol, studies have shown that insulin resistance is a more powerful predictor of cardiovascular disease. The damage starts even earlier through a process called glycation. When sugar stays in your bloodstream, it literally caramelizes, making molecules sticky and gumming up your proteins, blood vessels, and collagen. This accelerates aging, damages organs, messes with your kidneys, and stiffens your arteries. It’s a root issue that often gets overlooked when people focus solely on LDL or saturated fat.
The Cellular Breakdown: What’s Jamming the Signal?
At the heart of insulin resistance is a breakdown at the cellular level, specifically involving a tiny doorway on your muscle cells called the GLUT4 transporter. Think of your muscle cell as a garage, and glucose (sugar) as the car needing to get inside for fuel. Insulin is the remote control for that garage door.
In a healthy person, insulin signals GLUT4, the door opens, and glucose enters. But in insulin resistance, inflammation jams the signal from the remote. The glucose cars pile up outside in the bloodstream, causing glycation damage. So, what’s jamming the signal? Researchers point to fat-derived metabolites called diacylglycerols (DAGs). When your primary fat cells get overstuffed from over-nutrition (eating too much, or too many different types of fuel), they leak fatty acids into your muscles and liver. Inside the muscle, these fats are converted into DAGs – a thick, sticky sludge that gums up the receiver for the garage door signal. This sludge is what blocks the signal, preventing glucose from entering the cell.
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Your Insulin Resistance Toolkit: Actionable Solutions
Now for the good news: you can unjam these signals and reverse insulin resistance. Here’s a practical toolkit:
Step #1: The Post-Meal Walk
When your remote control isn’t working, you open the garage door manually. The energy crash after a meal is often your “remote” not working. A simple 15-20 minute walk after eating activates a secondary pathway (EMPK) that forces the GLUT4 doors open, bypassing insulin entirely. This is your manual override.
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